Berberine is extracted particularly from a shrub called Berberis. It belongs to a class of compounds called alkaloids and has a yellow color. Berberine has a long history in Chinese medicine for treating various ailments. Modern science has confirmed the bioactive compound has indeed a broad range of health benefits. It does this mainly by activating an enzyme inside cells called AMP-activated protein kinase (AMPK), which regulates the metabolism.
- Many studies show that berberine can significantly reduce blood sugar levels in individuals with type 2 diabetes. Berberine is very effective at lowering blood sugar and HbA1c, which are elevated in people with diabetes. It works as well as some pharmaceutical drugs.
- Berberine may also be effective as a weight loss supplement. Researchers believe that the weight loss is caused by improved function of fat-regulating hormones, such as insulin, adiponectin and leptin. Berberine also appears to inhibit the growth of fat cells at the molecular level.
- It lowers cholesterol and may reduce your risk of heart disease. Studies show that berberine reduces cholesterol and triglyceride levels, while raising HDL (the “good”) cholesterol. It may lower the risk of heart disease in the long-term.
- Berberine may also have other health benefits:
- Depression: Rat studies show that it may help fight depression.
- Cancer: Test tube and animal studies have shown that it can reduce the growth and spread of various different types of cancer.
- Antioxidant and anti-inflammatory: It has been shown to have potent antioxidant and anti-inflammatory effects in some studies
- Infections: It has been shown to fight harmful microorganisms, including bacteria, viruses, fungi and parasites
- Fatty liver: It can reduce fat build-up in the liver, which should help protect against non-alcoholic fatty liver disease (NAFLD).
- Heart failure: One study showed that it drastically improved symptoms and reduced risk of death in heart failure patients.
Many of these benefits need more research before firm recommendations can be made, but the current evidence is very promising.
A dose of 500 mg three times a day, before meals.
Berberine, Extract Powder (10:1). Contains no fillers.
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