L-Carnosine (beta-alanyl-L-histidine) is a dipeptide composed of the amino acids beta-alanine and histidine. Carnosine is an anti-glycating agent, which means is reduces the formation of glycation end-products. These substances appears to be important for emergence and deterioration caused by several degenerative diseases, e.g. atherosclerosis, diabetes, Alzheimer’s disease, chronic kidney failure. Another reason for the scientific interest is that chronic glycolysis appears to accelerate aging, which is quenched by L-Carnosine.
L-Carnosine is an anti-carbonylation agent that reduces irreversible protein modification induced by ROS (Reactive Oxygen Species), which is changes in the skin, including discoloration and keratinization. In practise, the agent helps to prevent skin collagen cross-linking, which leads to wrinkles and loss of elasticity.
The compound may also increase the Hayflick limit in human fibroblasts and appears to reduce the telomere shortening rate. In the body it acts as a strong antioxidant that fights off several destructive free radicals, such as superoxide, hydroxyl, peroxyl, and singlet oxygen. Because of these factors the substance is also considered as a senolytic geroprotector.
The dipeptide can support to chelate ionic metals, which means flushing heavy metals from the body.
- Prevent skin-aging and skin whitening effect
- As a possible senolytic to slow the rate of neurodegeneration
- Inhibits activity of Helicobacter pylori bacteria
- As a super-antioxidant protecting the stomach from environmental damage
- As an effective chelating agent
The typical daily amount of L-Carnosine is 1500 mg divided in three equal doses of 500 mg (under 1/4 teaspoon).
L-Carnosine 99% (Beta-Alanyl-L-Histidine).
The various effects are not guaranteed and results may vary due to several factors between different people.
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